PON1 Project Publications
Comparison of DNA methylation measurements from EPIC BeadChip and SeqCap targeted bisulfite sequencing in PON1 and nine additional candidate genes. Khodasevich D, Smith AR, Huen K, Eskenazi B, Cardenas A, Holland N [published online ahead of print, 2022 Jul 2]. Epigenetics. 2022;1-12. doi:10.1080/15592294.2022.2091818
PON1 DNA methylation and neurobehavior in Mexican-American children with prenatal organophosphate exposure.Huen, Karen & Solomon, Olivia & Kogut, Katherine & Eskenazi, Brenda & Holland, Nina. (2018). Environment international. 121. 31-40. 10.1016/j.envint.2018.08.044.
Relationship between expression and methylation of obesity-related genes in children.Davé V, Yousefi P, Huen K, Volberg V, Holland N. Mutagenesis. 2015;30(3):411-420. doi:10.1093/mutage/geu089
Recent progress in the genetics and epigenetics of paraoxonase: why it is relevant to children's environmental health.Holland N, Lizarraga D, Huen K. Curr Opin Pediatr. 2015;27(2):240-247. doi:10.1097/MOP.0000000000000192
PON1 as a model for integration of genetic, epigenetic, and expression data on candidate susceptibility genes.Huen K, Yousefi P, Street K, Eskenazi B, Holland N. Environ Epigenet. 2015;1(1):dvv003. doi:10.1093/eep/dvv003
Organophosphate pesticide exposure, PON1, and neurodevelopment in school-age children from the CHAMACOS study. Eskenazi B, Kogut K, Huen K, et al. Environ Res. 2014;134:149-157. doi:10.1016/j.envres.2014.07.001
Associations of PON1 and genetic ancestry with obesity in early childhood.Huen K, Harley K, Beckman K, Eskenazi B, Holland N. PLoS One. 2013;8(5):e62565. Published 2013 May 3. doi:10.1371/journal.pone.0062565
Cholinesterase and paraoxonase (PON1) enzyme activities in Mexican-American mothers and children from an agricultural community.Gonzalez V, Huen K, Venkat S, et al. J Expo Sci Environ Epidemiol. 2012;22(6):641-648. doi:10.1038/jes.2012.61
Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community.Huen K, Bradman A, Harley K, et al. Environ Res. 2012;117:8-16. doi:10.1016/j.envres.2012.05.005
Association of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American women. Harley KG, Huen K, Aguilar Schall R, et al. PLoS One. 2011;6(8):e23923. doi:10.1371/journal.pone.0023923
Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children. Huen K, Barcellos L, Beckman K, Rose S, Eskenazi B, Holland N. Environ Mol Mutagen. 2011;52(2):105-116. doi:10.1002/em.20567
Longitudinal changes in PON1 enzymatic activities in Mexican-American mothers and children with different genotypes and haplotypes.Huen K, Harley K, Bradman A, Eskenazi B, Holland N. Toxicol Appl Pharmacol. 2010;244(2):181-189. doi:10.1016/j.taap.2009.12.031
PON1 and neurodevelopment in children from the CHAMACOS study exposed to organophosphate pesticides in utero.Eskenazi B, Huen K, Marks A, et al. Environ Health Perspect. 2010;118(12):1775-1781. doi:10.1289/ehp.1002234
Developmental changes in PON1 enzyme activity in young children and effects of PON1 polymorphisms.Huen K, Harley K, Brooks J, et al. Environ Health Perspect. 2009;117(10):1632-1638. doi:10.1289/ehp.0900870
Validation of PON1 enzyme activity assays for longitudinal studies.Huen K, Richter R, Furlong C, Eskenazi B, Holland N. Clin Chim Acta. 2009;402(1-2):67-74. doi:10.1016/j.cca.2008.12.019
Determinants of PON1 variation in Mexican-American children and mothers. Huen K. University of California, Berkeley; 2009.
Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns. Holland N, Furlong C, Bastaki M, et al. Environ Health Perspect. 2006;114(7):985-991. doi:10.1289/ehp.8540
PON1 DNA methylation and neurobehavior in Mexican-American children with prenatal organophosphate exposure.Huen, Karen & Solomon, Olivia & Kogut, Katherine & Eskenazi, Brenda & Holland, Nina. (2018). Environment international. 121. 31-40. 10.1016/j.envint.2018.08.044.
Relationship between expression and methylation of obesity-related genes in children.Davé V, Yousefi P, Huen K, Volberg V, Holland N. Mutagenesis. 2015;30(3):411-420. doi:10.1093/mutage/geu089
Recent progress in the genetics and epigenetics of paraoxonase: why it is relevant to children's environmental health.Holland N, Lizarraga D, Huen K. Curr Opin Pediatr. 2015;27(2):240-247. doi:10.1097/MOP.0000000000000192
PON1 as a model for integration of genetic, epigenetic, and expression data on candidate susceptibility genes.Huen K, Yousefi P, Street K, Eskenazi B, Holland N. Environ Epigenet. 2015;1(1):dvv003. doi:10.1093/eep/dvv003
Organophosphate pesticide exposure, PON1, and neurodevelopment in school-age children from the CHAMACOS study. Eskenazi B, Kogut K, Huen K, et al. Environ Res. 2014;134:149-157. doi:10.1016/j.envres.2014.07.001
Associations of PON1 and genetic ancestry with obesity in early childhood.Huen K, Harley K, Beckman K, Eskenazi B, Holland N. PLoS One. 2013;8(5):e62565. Published 2013 May 3. doi:10.1371/journal.pone.0062565
Cholinesterase and paraoxonase (PON1) enzyme activities in Mexican-American mothers and children from an agricultural community.Gonzalez V, Huen K, Venkat S, et al. J Expo Sci Environ Epidemiol. 2012;22(6):641-648. doi:10.1038/jes.2012.61
Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community.Huen K, Bradman A, Harley K, et al. Environ Res. 2012;117:8-16. doi:10.1016/j.envres.2012.05.005
Association of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American women. Harley KG, Huen K, Aguilar Schall R, et al. PLoS One. 2011;6(8):e23923. doi:10.1371/journal.pone.0023923
Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children. Huen K, Barcellos L, Beckman K, Rose S, Eskenazi B, Holland N. Environ Mol Mutagen. 2011;52(2):105-116. doi:10.1002/em.20567
Longitudinal changes in PON1 enzymatic activities in Mexican-American mothers and children with different genotypes and haplotypes.Huen K, Harley K, Bradman A, Eskenazi B, Holland N. Toxicol Appl Pharmacol. 2010;244(2):181-189. doi:10.1016/j.taap.2009.12.031
PON1 and neurodevelopment in children from the CHAMACOS study exposed to organophosphate pesticides in utero.Eskenazi B, Huen K, Marks A, et al. Environ Health Perspect. 2010;118(12):1775-1781. doi:10.1289/ehp.1002234
Developmental changes in PON1 enzyme activity in young children and effects of PON1 polymorphisms.Huen K, Harley K, Brooks J, et al. Environ Health Perspect. 2009;117(10):1632-1638. doi:10.1289/ehp.0900870
Validation of PON1 enzyme activity assays for longitudinal studies.Huen K, Richter R, Furlong C, Eskenazi B, Holland N. Clin Chim Acta. 2009;402(1-2):67-74. doi:10.1016/j.cca.2008.12.019
Determinants of PON1 variation in Mexican-American children and mothers. Huen K. University of California, Berkeley; 2009.
Paraoxonase polymorphisms, haplotypes, and enzyme activity in Latino mothers and newborns. Holland N, Furlong C, Bastaki M, et al. Environ Health Perspect. 2006;114(7):985-991. doi:10.1289/ehp.8540
